FDA & Biotech: United Therapeutics says the FDA cleared it to proceed with a pig-derived, 10-gene-edited UHeart xenotransplant trial, starting with up to two patients and aiming to build toward a license application. Geopolitics & Inflation: Iran’s foreign minister warned the US could face rising economic pain if talks fail, as the Strait of Hormuz remains effectively constrained—fuel shocks are already showing up in inflation numbers. Local Economy & Jobs: A new aviation impact study says Billings Logan Airport supports about 4,585 jobs and $265m in payroll, underlining how air travel ripples into tourism and healthcare. Trade Policy Shock: India restricted silver imports after a jump in precious-metals duties, while gold and silver prices surged in the week following the higher import duty. Business Climate: Colorado tech leaders are pushing back on red tape, arguing companies and capital are being driven away. Public Sector & Costs: Nigeria’s inflation hit 15.69% in April, and the Lagos Chamber of Commerce urged faster consolidation of reforms and FX stabilization. Municipal Services: Hyderabad’s Malkajgiri is pushing for 100% door-to-door garbage collection, even in hilly areas.